What Is The Main Cause of Psoriasis ? How to Treat Psoriasis Naturally ?
Psoriasis is a chronic, autoimmune-mediated inflammatory disease that is predominantly initiated and perpetuated by T cells. Keratinocyte (KC) proliferation, infiltration of inflammatory cells and angiogenesis are the mainly characteristic histopathology manifestation of psoriasis. The prevalence of psoriasis ranges from 0.1% to 11.4% in different countries; it affects more than 100 million people worldwide , and its incidence is increasing year by year. Psoriasis has a high recurrence rate and is a lifelong disorder that severely reduces the life quality of patients, creating both a physical and psychological burden. Although the exact pathogenesis of psoriasis remains unclear, it is now widely accepted that gene-gene and environment-gene interactions may affect its onset, manifestation and clinical course . Susceptibility genes for psoriasis have been widely studied by various methods, especially genome-wide association studies (GWAS), to be...