Getting Pregnant with PCOS Quickly

Incidence of polycystic ovarian syndrome (PCOs) according toRotterdam criteria is 19.5%. It protests as infertility, men-strual problems, hirsutism, acne, obesity and worsenedhealth-related quality of life. In this syndrome, byincreasing the concentrations of estrogen and probably reduc-ing SHBG, hypothalamus and pituitary sensitivity change andlevel of LH enhances, however the FSH remains normal ordiminishes. Both autosomal and X-linked dominant modesof inheritance need to describe the familial clustering of PCOs women Although patients with polycystic ovary respond ade-quately to ovulation, some of them require Assisted Reproduc-tive Technology (ART). However, there are some reportson other possible ways of influencing ovarian function by gonadotropin, growth hormone, glucocorticostroids, low dose aspirin, metformin and also dexamethasone. Dexam-ethasone was used for the first time in 1953. It inhibits theestradiol activity directly, affects the pituitary gland and les-sens adrenal androgen level, therefore increases the follicular growth.It seems dexamethasone reduced the influences of adrenalandrogenism on follicle growth. Harlow et al. showedthe significant increase of intra follicle cortisol after ovulationexplains the role of steroids in oocyte maturation and ovulation.

In recent study, regarding the improvement of pregnancyrate and number of embryos in PCOs women who received dexamethasone, the results recommend to add this useful medicineto IVF/ICSI treatment to reach proper outcome. A well-designed study is suggested to compare the effect of dexam-ethasone on PCOs women candidate for IVF/ICST in variousbody mass indexes (BMI) (NEXT: Pregnancy Success Stories – Natural Way To Get Pregnant Quickly)